Doses approximately four hundred mg orally when per day are already well-tolerated, but there's no dependable evidence of extra reward over and above that of two hundred mg orally as soon as on a daily basis.

最近の研究により、上述の通り脳ペプチドの１つであるオレキシンが作用発現に関与する可能性が示唆されている。オレキシン神経は、視床下部を起始部として、覚醒の維持制御に関与する部位を含め、脳内の広い部位に神経を投射している。これらの神経の活性化により、投射部位でドパミンやノルアドレナリンが増加する。オレキシン系を欠損する動物では、ナルコレプシーに近い症状が見られる。モダフィニルはオレキシン神経を賦活化させ、この結果覚醒を促進させると考えられる。しかしながら、オレキシン受容体が欠損した遺伝子改変犬での研究においても、モダフィニルはこれらの動物で覚醒促進効果を示したため、モダフィニルの作用発現にはオレキシンの活性化は必須ではないものと推測される。

A special MedGuide is going to be provided to you via the pharmacist with Each and every prescription and refill. Be sure to look at this information and facts meticulously each time.

This medication may very well be prescribed for other uses; request your physician or pharmacist To find out more.

Retailer modafinil in a secure spot making sure that no person else might take it accidentally or on objective. Keep track of what number of tablets are still left so you will know if any are missing.

This medication may perhaps trigger serious pores and skin reactions. They are able to materialize weeks to months after commencing the medication. Get hold of your health care company right away when you see fevers or flu-like signs by using a rash.

If you're taking modafinil to deal with sleepiness caused by obstructive snooze apnea, You may additionally be taken care of which has a continuous positive airway pressure (CPAP) equipment.

Misuse signifies taking medication in a means apart from how it was prescribed. Just take modafinil particularly as prescribed. Notify your healthcare supplier when you feel that modafinil isn't Doing work. 

Some Unintended effects could be significant. For those who knowledge any of these indications, connect with your health practitioner quickly:

Studies also recommend that modafinil is a powerful remedy for both equally the fatigue and memory impairment connected with a number of sclerosis.‍[27]

If you take modafinil to help with obstructive snooze apnea, it is important to continue your other prescribed slumber apnea treatments, such as employing a continual positive airway tension (CPAP) device, Unless of course your Health care company lets you know to not. 

Making use of alcohol or tobacco with specific medicines can also result in interactions to take place. Focus on with your Health care Specialist using your medication with food stuff, alcohol, or tobacco.

If you make an effort to import therapeutic merchandise unlawfully you might be topic to criminal prosecution website with penalties together with jail time and sizeable financial penalties.

If you pass up a dose, acquire it the moment you don't forget. If it is almost time on your subsequent dose or close to bedtime, skip the missed dose and only acquire another dose. Will not get double or excess doses. Having a dose way too near bedtime might help it become more durable for you to rest.